Measles Research Today is a free monthly online journal that collates and summarizes the latest research about Measles, including details on german measles, symptoms, vaccine, treatment, rubella.

The Clinical Epidemiology of Pediatric Patients With Measles From 2000 to 2009 in Shanghai, China.

Ye Y, Wang W, Wang X, Yu H

The Children's Hospital of Fudan University, Shanghai 201102,People's Republic of China.

Measles remains a leading vaccine-preventable cause of child mortality worldwide. The incidence has increased recently in some areas. The authors retrospectively analyzed the epidemiological and clinical characteristics of 2473 measles patients in Shanghai from 2000 to 2009. There were 1909 measles cases during 2005-2009 (group II), whereas only 564 cases were reported during 2000-2004 (group I). In total, 60.87% patients in group II were younger than 9 months, which was significantly higher than that in group I (35.28%; P < .001). More complications, death cases, and less atypical rashes were found in recent years. In addition, 2181 of all the 2473 patients (88.19%) and 1112 of 1328 hospitalized children (83.73%) had not been vaccinated; most of them were immigrants. The results indicated that the rising number of immigrants accounted for the increased measles morbidity in Shanghai. The tendency of more young patients and increased complications suggest that some adjustments might be needed in vaccination administration and therapeutic strategy.

Published 12 May 2011 in Clin Pediatr (Phila).
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Articles on Measles published 10 May 2011:

Changes in measles seroepidemiology of healthcare workers in southern Taiwan.   Epidemiol Infect.

SUMMARYTo assess the measles seroepidemiology of healthcare workers (HCWs), from 2004 to 2009 all newly recruited staff at a university hospital in Taiwan, were tested for specific immunoglobulin G antibodies for measles virus using enzyme-linked immunosorbent assays. A total of 1584 HCWs were included. The positivity rate of measles antibody for physicians and nurses was about 90%. The positivity of measles antibody in different age groups was 78·1%, 93·9% and 94·2% for 20-29, 30-39 and ... [Abstract] [Full-text]

Articles on Measles published 9 May 2011:

Effectiveness assessment of vaccination policy against measles epidemic in Japan using an age-time two-dimensional mathematical model.   Environ Health Prev Med.

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The effect of live, attenuated measles vaccine and measles infection on measles antibody levels in serum and CSF of patients with multiple sclerosis or clinically isolated syndrome.   J Neuroimmunol.

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Articles on Measles published 6 May 2011:

Measles virus C protein suppresses gamma-activated factor formation and virus-induced cell growth arrest.   Virology, 414(1): 74-82.

Measles virus (MeV) produces two accessory proteins, V and C, from the P gene. These accessory proteins have been reported to contribute to efficient virus proliferation through the modulation of host cell events. Our previous paper described that Vero cell-adapted strains of MeV led host cells to growth arrest through the upregulation of interferon regulatory factor 1 (IRF-1), and wild strains did not. In the present study, we found that C protein expression levels varied among MeV strains in ... [Abstract] [Full-text]

Articles on Measles published 5 May 2011:

Canine Distemper Matrix Protein Modulates Particle Infectivity, Particle Composition, and Envelope Distribution in Polarized Epithelial Cells, and Virulence.   J Virol.

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Articles on Measles published 4 May 2011:

Detection of platelet-binding anti-measles and anti-rubella virus IgG antibodies in infants with vaccine-induced thrombocytopenic purpura.   Vaccine.

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A large observational study to concurrently assess persistence of measles specific B-cell and T-cell immunity in individuals following two doses of MMR vaccine.   Vaccine.

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